Incorporation of unusual and non natural amino acids in peptides

Instead of 20 natural L-amino acids there are many non-natural or unusual amino acids available that can be used into synthetic peptides. These unnatural building blocks can be incorporated into custom peptides for different application such pharmacologically active ingredients, conformational constraints, combinatorial libraries and stabilization of secondary structure. GenPep offers number of different non-natural amino acids, which routinely inserted into peptides. GenPep Pharmaceuticals offers peptides with the unnatural amino acids which may include D-amino acids, N-methyl amino acids, homo amino acids, alpha methyl amino acids, non-natural side chain amino acids. D-amino acids are mirror image of natural occurring L-isomers, they are mostly used to resist enzymatic degradations.